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| Nomenclature |
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Symbol:
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Pax9tm1Rbal
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Name:
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paired box gene 9;
targeted mutation 1, R Balling
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MGI ID: |
MGI:1857887 |
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Synonyms: |
Pax9lacZ |
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Gene:
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Pax9
Location:
Chr12:56691767-56712822 bp, + strand
Genetic Position: Chr12,
24.53 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:49857
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: The endogenous start codon as well as the exon encoding the paired box was replaced a LacZ and PGK-neomycin based cassette. Lack of wild-type protein was confirmed by Western analysis in homozygous mutant embryos. (J:49857)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pax9 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:49857
Peters H et al.,
"Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities."
Genes Dev 1998 Sep 1;12(17):2735-47
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All: |
10 reference(s)
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Analysis Tools
