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| Nomenclature |
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Symbol:
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Sod1tm1Leb
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Name:
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superoxide dismutase 1, soluble;
targeted mutation 1, Russell M Lebovitz
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MGI ID: |
MGI:1857873 |
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Synonyms: |
Cu,Zn-SOD-, CuZnSOD-, SOD1-, SOD1m1BCM |
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Gene:
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Sod1
Location:
Chr16:90220742-90226322 bp, + strand
Genetic Position: Chr16,
51.56 cM, cytoband B5-C3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:64299
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Parent Cell Line:
| AB2.1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Replacement of exons 1 and 2 with a PGK-hprt expression cassette. Protein was not detected in brain of homozygous mutant mice. (J:64299)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:64299
Matzuk MM et al.,
"Ovarian function in superoxide dismutase 1 and 2 knockout mice."
Endocrinology 1998 Sep;139(9):4008-11
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All: |
34 reference(s)
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Analysis Tools
