|
|
| Nomenclature |
|
Symbol:
|
Foxc1tm1Blh
|
|
Name:
|
forkhead box C1;
targeted mutation 1, Brigid L Hogan
|
|
MGI ID: |
MGI:1857869 |
|
Synonyms: |
Foxc1-, Foxc1Lacz, Mf1-, Mf1lacZ |
|
Gene:
|
Foxc1
Location:
Chr13:31806691-31810643 bp, + strand
Genetic Position: Chr13,
13.52 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:48079
|
|
Parent Cell Line:
| TL1/TL-1 (ES Cell) |
|
Strain of Origin:
|
129S6/SvEvTac
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Reporter) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A lacZ- neomycin resistance cassette replaced sequences encoding amino acids 90-553 and most of the 3' untranslated region. A beta galactosidase fusion protein is expressed from this allele. (J:48079)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Foxc1 Mutation:
|
1 strain or line available |
|
| References |
|
Original: |
J:48079
Kume T et al.,
"The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus."
Cell 1998 Jun 12;93(6):985-96
|
|
All: |
18 reference(s)
|
|
Analysis Tools
