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| Nomenclature |
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Symbol:
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Hoxdtm3Ddu
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Name:
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homeobox D cluster;
targeted mutation 3, Denis Duboule
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MGI ID: |
MGI:1857854 |
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Synonyms: |
Hoxd12tm1Ddu, HoxDRXI, L2 |
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Gene:
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Hoxd
Location:
unknown
Genetic Position: Chr2,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:47900
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Deletion |
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Mutation details: A neomycin resistance cassette flanked by loxP sites replaced the regulatory element, RXI, located in the intergenic region between Hoxd12 and Hoxd13. This selection cassette was excised by breeding mice carrying this mutation with a Cre deleter strain. (J:47900)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hoxd Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:47900
Herault Y et al.,
"Genetic analysis of a Hoxd-12 regulatory element reveals global versus local modes of controls in the HoxD complex."
Development 1998 May;125(9):1669-77
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All: |
3 reference(s)
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Analysis Tools
