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| Nomenclature |
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Symbol:
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Itga3tm1Jak
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Name:
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integrin alpha 3;
targeted mutation 1, Jordan A Kreidberg
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MGI ID: |
MGI:1857792 |
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Synonyms: |
alpha3-, alpha3beta1-deficient, alpha 3 beta 1 integrin-deficient |
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Gene:
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Itga3
Location:
Chr11:95044474-95076801 bp, - strand
Genetic Position: Chr11,
59.01 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:36831
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A neomycin resistance cassette was inserted into the site that corresponds to cDNA nucleotide 1065. (J:36831)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Itga3 Mutation:
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13 strains or lines available |
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| References |
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Original: |
J:36831
Kreidberg JA et al.,
"Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis."
Development 1996 Nov;122(11):3537-47
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All: |
22 reference(s)
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Analysis Tools
