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| Nomenclature |
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Symbol:
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Acvr2btm1Enl
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Name:
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activin receptor IIB;
targeted mutation 1, En Li
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MGI ID: |
MGI:1857709 |
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Synonyms: |
ActRIIB-, Acvr2b-, IIB-KO |
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Gene:
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Acvr2b
Location:
Chr9:119402501-119433515 bp, + strand
Genetic Position: Chr9,
71.33 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:42018
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 1.4kb genomic fragment containing two exons encoding the transmembrane and part of the kinase domains was replaced by a neomycin resistance cassette. (J:42018)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acvr2b Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:42018
Oh SP et al.,
"The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse."
Genes Dev 1997 Jul 15;11(14):1812-26
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All: |
15 reference(s)
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Analysis Tools
