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| Nomenclature |
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Symbol:
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Smad5tm1Zuk
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Name:
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SMAD family member 5;
targeted mutation 1, Martin M Matzuk
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MGI ID: |
MGI:1857666 |
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Synonyms: |
smad5m1 |
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Gene:
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Smad5
Location:
Chr13:56703010-56742377 bp, + strand
Genetic Position: Chr13,
30.12 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:53293
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Parent Cell Line:
| AB2.1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-hprt expression cassette replaced exon 2 and its flanking sequences. In addition, a transcriptional terminator sequence was introduced into intron 1. (J:53293)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:53293
Chang H et al.,
"Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects."
Development 1999 Apr;126(8):1631-42
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All: |
13 reference(s)
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Analysis Tools
