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| Nomenclature |
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Symbol:
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Pitx1tm1Jdr
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Name:
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paired-like homeodomain transcription factor 1;
targeted mutation 1, Jaques Drouin
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MGI ID: |
MGI:1857659 |
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Synonyms: |
Pitxtm1, Ptx1- |
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Gene:
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Pitx1
Location:
Chr13:55825054-55836192 bp, - strand
Genetic Position: Chr13,
30.06 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:52671
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exon 2 of this gene containing a homeodomain was replaced with a PGKneo-derived cassette via homologous recombination. Gene expression was not detected in Northern blot of mandibles from homozygous mutant embryos. (J:52671)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pitx1 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:52671
Lanctot C et al.,
"Hindlimb patterning and mandible development require the Ptx1 gene."
Development 1999 May;126(9):1805-10
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All: |
6 reference(s)
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Analysis Tools
