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| Nomenclature |
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Symbol:
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Hand2tm1Dsr
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Name:
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heart and neural crest derivatives expressed transcript 2;
targeted mutation 1, Deepak Srivastava
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MGI ID: |
MGI:1857639 |
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Synonyms: |
dHANDnull |
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Gene:
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Hand2
Location:
Chr8:57320983-57324517 bp, + strand
Genetic Position: Chr8,
29.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:40768
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A neomycin resistance cassette replaced the entire gene. (J:40768)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Hand2 Mutation:
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0 strains or lines available |
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| References |
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Original: |
J:40768
Srivastava D et al.,
"Regulation of cardiac mesodermal and neural crest development by the bHLH transcription factor, dHAND [see comments] [published erratum appears in Nat Genet 1997 Aug;16(4):410]"
Nat Genet 1997 Jun;16(2):154-60
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All: |
18 reference(s)
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Analysis Tools
