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| Nomenclature |
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Symbol:
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Cryga1Neu
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Name:
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crystallin, gamma A;
1 Neuherberg
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MGI ID: |
MGI:1857595 |
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Synonyms: |
ENU-436 |
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Gene:
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Cryga
Location:
Chr1:65100389-65103373 bp, - strand
Genetic Position: Chr1,
32.84 cM
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Mutation
origin |
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Strain of Origin:
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(101 x C3H)F1
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: A point mutation in exon 2 introduces an A to G transition at position 230 of the encoded cDNA. This mutation is predicted to lead to the amino acid substitution of aspartic acid to glycine at position 77, affecting the connecting peptide between the second and third Greek-key motif. (J:50319)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cryga Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:21950
Favor J,
"A comparison of the dominant cataract and recessive specific-locus mutation rates induced by treatment of male mice with ethylnitrosourea."
Mutat Res 1983 Aug;110(2):367-82
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All: |
4 reference(s)
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Analysis Tools
