|
|
| Nomenclature |
|
Symbol:
|
Dbhtm1Rpa
|
|
Name:
|
dopamine beta hydroxylase;
targeted mutation 1, Richard D Palmiter
|
|
MGI ID: |
MGI:1857556 |
|
Synonyms: |
DA-, Dbh-, DBH-, DBH-KO |
|
Gene:
|
Dbh
Location:
Chr2:27165233-27183200 bp, + strand
Genetic Position: Chr2,
19.29 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:24414
|
|
Parent Cell Line:
| AB1 (ES Cell) |
|
Strain of Origin:
|
129S7/SvEvBrd-Hprt+
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neomycin resistance cassette replaced 3.4kb of sequence including the proximal promoter and first exon. (J:24414)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:24414
Thomas SA et al.,
"Noradrenaline is essential for mouse fetal development."
Nature 1995 Apr 13;374(6523):643-6
|
|
All: |
52 reference(s)
|
|
Analysis Tools
