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| Nomenclature |
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Symbol:
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Wlds
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Name:
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wallerian degeneration;
Wallerian degeneration slow
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MGI ID: |
MGI:1857538 |
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Synonyms: |
Wlds |
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Gene:
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Wld
Location:
unknown
Genetic Position: Chr4,
Syntenic
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Mutation
origin |
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Strain of Origin:
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C57BL/6Ola
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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Mutation details: The underlying mutation is an 85-kb tandem triplication on chromosome 4. This triplication results in the expression of an abnormal transcript that encodes a fusion of the N-terminal fragment of ubiquitination factor E4B (Ube4b) fused to nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1). (J:49401, J:65178, J:72936, J:75678)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:15229
Lyon MF et al.,
"A gene affecting Wallerian nerve degeneration maps distally on mouse chromosome 4."
Proc Natl Acad Sci U S A 1993 Oct 15;90(20):9717-20
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All: |
95 reference(s)
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Analysis Tools
