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| Nomenclature |
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Symbol:
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Gli2tm1Alj
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Name:
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GLI-Kruppel family member GLI2;
targeted mutation 1, Alexandra L Joyner
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MGI ID: |
MGI:1857509 |
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Synonyms: |
Gli2-, Gli2zfd |
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Gene:
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Gli2
Location:
Chr1:118834132-119053619 bp, - strand
Genetic Position: Chr1,
52.17 cM, cytoband E2-E4
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:38381
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance cassette replaced 2.4 kb of the gene, resulting in the deletion of exons that encode the zinc fingers 3 - 5 of the protein and 71 amino acid residues carboxyl to these zinc fingers. (J:38381, J:49164)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Gli2 Mutation:
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97 strains or lines available |
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| References |
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Original: |
J:38381
Mo R et al.,
"Specific and redundant functions of Gli2 and Gli3 zinc finger genes in skeletal patterning and development."
Development 1997 Jan;124(1):113-23
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All: |
79 reference(s)
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Analysis Tools
