|
|
| Nomenclature |
|
Symbol:
|
Fbn1Tsk
|
|
Name:
|
fibrillin 1;
tight skin
|
|
MGI ID: |
MGI:1857348 |
|
Synonyms: |
TSK |
|
Gene:
|
Fbn1
Location:
Chr2:125300594-125507993 bp, - strand
Genetic Position: Chr2,
61.38 cM, cytoband F
|
|
Fbn1Tsk/Fbn1+ skin exhibits abnormal organization and distribution of microfibrillar arrays
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Strain of Origin:
|
B10.D2/(58N)Sn
|
|
Mutation
description |
|
Allele
Type: | |
Spontaneous |
|
Mutation: | |
Duplication |
| |
|
Mutation details: This allele harbors a 30 to 40kb genomic tandem duplication within the Fbn1 gene that results in a larger than normal in-frame transcript produced at normal levels. (J:32931, J:45733, J:55886)
|
|
Inheritance: | |
Semidominant |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
|
Notes |
Genbank ID for this allele: AF007248
|
| References |
|
Analysis Tools
