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| Nomenclature |
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Symbol:
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Mpv17
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Name:
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MpV17 mitochondrial inner membrane protein;
Mpv17 retroviral insertion, kidney disease mutant
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MGI ID: |
MGI:1857300 |
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Synonyms: |
MPV- |
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Gene:
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Mpv17
Location:
Chr5:31140660-31158153 bp, - strand
Genetic Position: Chr5,
17.12 cM
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, gene disruption) |
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Mutation: | |
Insertion |
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Mutation details: The Mpv17 mutation was generated by infection of CFW preimplantation mouse embryos with a recombinant retrovirus, MPSVneo, which carries a neo gene and is a replication-defective derivative of the myeloproliferative sarcoma virus, a Moloney murine leukemia virus-related RNA virus. (J:10661)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:10661
Weiher H et al.,
"Transgenic mouse model of kidney disease: insertional inactivation of ubiquitously expressed gene leads to nephrotic syndrome."
Cell 1990 Aug 10;62(3):425-34
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All: |
15 reference(s)
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Analysis Tools
