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| Nomenclature |
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Symbol:
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Hbb-b2tm1Unc
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Name:
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hemoglobin, beta adult minor chain;
targeted mutation 1, University of North Carolina
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MGI ID: |
MGI:1857296 |
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Synonyms: |
Hbbth-3, Hbbth3 |
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Gene:
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Hbb-b2
Location:
unknown
Genetic Position: Chr7,
54.85 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:30155
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Parent Cell Line:
| E14TG2a (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intergenic deletion |
| |
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Mutation details: Hbb-b1 and Hbb-b2 were deleted using a two-step "plug and socket" method which leaves an hprt gene integrated in the genome. (J:20916)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:30155
Yang B et al.,
"A mouse model for beta 0-thalassemia."
Proc Natl Acad Sci U S A 1995 Dec 5;92(25):11608-12
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All: |
27 reference(s)
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Analysis Tools
