|
|
| Nomenclature |
|
Symbol:
|
Icam1tm1Jcgr
|
|
Name:
|
intercellular adhesion molecule 1;
targeted mutation 1, Jose Carlos Gutierrez Ramos
|
|
MGI ID: |
MGI:1857292 |
|
Synonyms: |
ICAM-1-, ICAM-1-deficient, ICAMtm1-jcgr |
|
Gene:
|
Icam1
Location:
Chr9:21015960-21028797 bp, + strand
Genetic Position: Chr9,
7.69 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:18743
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A neomycin resistance cassette was inserted into exon 4 of the gene. While King, et. al. (J:25530) reported the potential for the production of functional proteins arising from alternative transcripts, corresponding signals were undetected by immunohistochemical analysis of homozygous mutant mice. (J:18743)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:18743
Xu H et al.,
"Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice."
J Exp Med 1994 Jul 1;180(1):95-109
|
|
All: |
58 reference(s)
|
|
Analysis Tools
