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Ifngr1tm1Agt
Targeted Allele Detail

Nomenclature
Symbol: Ifngr1tm1Agt
Name: interferon gamma receptor 1; targeted mutation 1, Michel Aguet
MGI ID: MGI:1857286
Synonyms: G129, IFN-gamma R-, IFN-gammaR-, IFN-gamma R0, IFN-gammaR0, IFN-gammaR1-, IFN-gammaRalpha_, IFN-gamma-R KO, IFN-gammaR KO, IFNgammaR KO, Ifngr-, Ifngr1-, IFNgR KO, IFn type II receptor
Gene: Ifngr1   Location: Chr10:19591949-19610229 bp, + strand    Genetic Position: Chr10, 8.49 cM
Trpm2tm1.1Alp/Trpm2tm1.1Alp and Ifngr1tm1Agt/Ifngr1tm1Agt mice exhibit increased susceptibility to bacterial infection

Show the 1 image(s) involving this allele.

Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:63815
Parent Cell Line: AB1 (ES Cell)
Strain of Origin: 129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:   Targeted (knock-out)
Mutation:   Insertion
 
Mutation details
Inheritance:   Recessive
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Ifngr1 Mutation: 5 strains or lines available
References
Original: J:63815 Huang S et al., "Immune response in mice that lack the interferon-gamma receptor [see comments]" Science 1993 Mar 19;259(5102):1742-5
All: 351 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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Send questions and comments to User Support. 		last database update
05/08/2013
MGI 5.13 		The Jackson Laboratory