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| Nomenclature |
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Symbol:
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Tcrbtm1Mom
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Name:
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T cell receptor beta chain;
targeted mutation 1, Peter Mombaerts
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MGI ID: |
MGI:1857256 |
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Synonyms: |
beta-, CBeta-, TCRb-, TCRbeta-, TCR-Cbeta- |
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Gene:
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Tcrb
Location:
unknown
Genetic Position: Chr6,
cytoband A-C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:22591
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: 15kb of sequence was replaced with a PGK-neo cassette. The deletion included one of the two D gene segments, ten of the twelve J gene segments, and both constant gene segments. (J:22591)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:22591
Mombaerts P et al.,
"Creation of a large genomic deletion at the T-cell antigen receptor beta-subunit locus in mouse embryonic stem cells by gene targeting."
Proc Natl Acad Sci U S A 1991 Apr 15;88(8):3084-7
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All: |
301 reference(s)
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Analysis Tools
