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| Nomenclature |
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Symbol:
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Lrpap1tm1Her
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Name:
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low density lipoprotein receptor-related protein associated protein 1;
targeted mutation 1, Joachim Herz
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MGI ID: |
MGI:1857214 |
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Synonyms: |
RAP- |
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Gene:
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Lrpap1
Location:
Chr5:35091490-35105766 bp, - strand
Genetic Position: Chr5,
18.01 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:43736
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Parent Cell Line:
| Other (see notes) (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin resistance cassette was inserted into sequences that encode the leader peptide. Immunoblot analysis of liver and brain did not detect the encoded protein in homozygous animals. (J:43736)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
ES cell line = JH1 or AB1 (129S7/SvEvBrd-Hprt+).
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| References |
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Original: |
J:43736
Willnow TE et al.,
"Functional expression of low density lipoprotein receptor-related protein is controlled by receptor-associated protein in vivo."
Proc Natl Acad Sci U S A 1995 May 9;92(10):4537-41
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All: |
13 reference(s)
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Analysis Tools
