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| Nomenclature |
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Symbol:
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Il4tm1Cgn
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Name:
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interleukin 4;
targeted mutation 1, University of Cologne
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MGI ID: |
MGI:1857194 |
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Synonyms: |
IL-4-, IL4-, IL-4KO, IL-4 KO, IL4T, IL-4T-, IL4tm1cgn129 |
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Gene:
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Il4
Location:
Chr11:53602982-53618669 bp, - strand
Genetic Position: Chr11,
31.97 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:704
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A translational stop codon and a neomycin resistance gene were inserted into the first exon of the gene. (J:704)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:704
Kuhn R et al.,
"Generation and analysis of interleukin-4 deficient mice."
Science 1991 Nov 1;254(5032):707-10
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All: |
165 reference(s)
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