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| Nomenclature |
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Symbol:
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Fyntm1Sor
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Name:
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Fyn proto-oncogene;
targeted mutation 1, Philippe Soriano
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MGI ID: |
MGI:1857172 |
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Synonyms: |
fyn- |
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Gene:
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Fyn
Location:
Chr10:39368855-39565381 bp, + strand
Genetic Position: Chr10,
20.51 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:2242
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Replacement of a 3kb fragment containing the first coding exon of the gene with a neomycin cassette. (J:2242, J:97095)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:2242
Stein PL et al.,
"pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells."
Cell 1992 Sep 4;70(5):741-50
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All: |
117 reference(s)
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