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Fyntm1Sor
Targeted Allele Detail

Nomenclature
Symbol: Fyntm1Sor
Name: Fyn proto-oncogene; targeted mutation 1, Philippe Soriano
MGI ID: MGI:1857172
Synonyms: fyn-
Gene: Fyn   Location: Chr10:39368855-39565381 bp, + strand    Genetic Position: Chr10, 20.51 cM
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:2242
Parent Cell Line: AB1 (ES Cell)
Strain of Origin: 129S7/SvEvBrd-Hprt+
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    Replacement of a 3kb fragment containing the first coding exon of the gene with a neomycin cassette. (J:2242, J:97095)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Fyn Mutation: 12 strains or lines available
References
Original: J:2242 Stein PL et al., "pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells." Cell 1992 Sep 4;70(5):741-50
All: 117 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory