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| Nomenclature |
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Symbol:
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En1tm1Alj
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Name:
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engrailed 1;
targeted mutation 1, Alexandra L Joyner
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MGI ID: |
MGI:1857163 |
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Synonyms: |
En-1hd |
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Gene:
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En1
Location:
Chr1:120602418-120609296 bp, + strand
Genetic Position: Chr1,
52.74 cM, cytoband C2-qter
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:19212
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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A neomycin selection cassette replaced 0.85 kb of exon 2, which encodes part of the homeobox domain. (J:19212)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:19212
Wurst W et al.,
"Multiple developmental defects in Engrailed-1 mutant mice: an early mid-hindbrain deletion and patterning defects in forelimbs and sternum."
Development 1994 Jul;120(7):2065-75
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All: |
20 reference(s)
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Analysis Tools
