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| Nomenclature |
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Symbol:
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Cd4tm1Knw
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Name:
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CD4 antigen;
targeted mutation 1, Barbara B Knowles
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MGI ID: |
MGI:1857143 |
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Synonyms: |
CD4-, CD4D |
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Gene:
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Cd4
Location:
Chr6:124864692-124888221 bp, - strand
Genetic Position: Chr6,
59.17 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:48775
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Parent Cell Line:
| CCE/EK.CCE (ES Cell) |
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Strain of Origin:
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129S/SvEv-Gpi1c
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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A neomycin resistance gene was inserted into exon 5. (J:48775)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:48775
McCarrick JW 3rd et al.,
"Positive-negative selection gene targeting with the diphtheria toxin A-chain gene in mouse embryonic stem cells."
Transgenic Res 1993 Jul;2(4):183-90
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All: |
24 reference(s)
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