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| Nomenclature |
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Symbol:
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Bmp4tm1Blh
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Name:
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bone morphogenetic protein 4;
targeted mutation 1, Brigid L Hogan
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MGI ID: |
MGI:1857137 |
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Synonyms: |
Bmp4-, Bmp4delta, Bmp4tm1, Bmp-4tm1blh |
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Gene:
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Bmp4
Location:
Chr14:46383520-46390669 bp, - strand
Genetic Position: Chr14,
23.95 cM
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Anterior eye segment abnormalities in Bmp4tm1Blh/Bmp4+ mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:28717
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin selection cassette replaced a genomic fragment containing all of the coding sequence of the gene after the seventh codon of exon 1. An oligonucleotide encoding a stop codon in all three reading frames was also inserted into exon 2. (J:28717)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:28717
Winnier G et al.,
"Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse."
Genes Dev 1995 Sep 1;9(17):2105-16
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All: |
34 reference(s)
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Analysis Tools
