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| Nomenclature |
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Symbol:
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Ass1tm1Bay
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Name:
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argininosuccinate synthetase 1;
targeted mutation 1, Baylor College of Medicine
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MGI ID: |
MGI:1857131 |
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Synonyms: |
Ass- |
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Gene:
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Ass1
Location:
Chr2:31470207-31520672 bp, + strand
Genetic Position: Chr2,
21.81 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:18326
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Parent Cell Line:
| AB1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprt+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A neomycin resistance cassette was inserted into exon 4 of the gene. Activity assays in liver extracts from homozygous mice demostrated the absence of the functional protein. (J:18326)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:18326
Patejunas G et al.,
"Generation of a mouse model for citrullinemia by targeted disruption of the argininosuccinate synthetase gene."
Somat Cell Mol Genet 1994 Jan;20(1):55-60
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All: |
4 reference(s)
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Analysis Tools
