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| Nomenclature |
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Symbol:
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Whrnwi
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Name:
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whirlin;
whirler
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MGI ID: |
MGI:1857090 |
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Synonyms: |
wi |
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Gene:
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Whrn
Location:
Chr4:63414910-63495991 bp, - strand
Genetic Position: Chr4,
33.97 cM, cytoband C1
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Mutation
origin |
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Strain of Origin:
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STOCK a Tyrp1b Myo5ad Oca2p Ednrbs
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Intragenic deletion |
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Mutation details: The mutation was identified as a 526 bp deletion encompassing the first putative methionine of the short C-terminal isoform and part of the long isoform. This creates a frameshift resulting in premature termination of the long isoform before the third PDZ domain. (J:86904)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
They have defects of the membranous labyrinth similar to those of Myo15 (M.S. Deol, personal communication).
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| References |
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Original: |
J:269
Lane PW,
"Whirler mice, a recessive behavior mutation in linkage group VIII"
J Hered 1963 Nov-Dec;54():263-6
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All: |
18 reference(s)
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Analysis Tools
