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| Nomenclature |
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Symbol:
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Tbx6rv
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Name:
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T-box 6;
rib-vertebrae
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MGI ID: |
MGI:1857025 |
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Synonyms: |
rv |
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Gene:
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Tbx6
Location:
Chr7:126781483-126785560 bp, + strand
Genetic Position: Chr7,
69.25 cM
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Tbx6rv/Tbx6rv and Tbx6rv/+
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutations: | |
Insertion, Duplication |
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Mutation details: This hypomorphic allele contains a rearrangement in the promoter region. A 182 bp insertion 240 bp upstream of the translation initiation site includes part of exon 1, intron 1, and a portion of exon 2 in inverted orientation. Whole mount in situ hybridisation detected variable and less abundant transcript expression in homozygous mutant E9.5 embryos. (J:80767)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:8119
Theiler K et al.,
"Development of rib-vertebrae: a new mutation in the house mouse with accessory caudal duplications."
Anat Embryol (Berl) 1985;173(1):111-6
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All: |
6 reference(s)
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Analysis Tools
