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| Nomenclature |
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Symbol:
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Dsg4lah
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Name:
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desmoglein 4;
lanceolate hair
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MGI ID: |
MGI:1856929 |
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Gene:
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Dsg4
Location:
Chr18:20436175-20471821 bp, + strand
Genetic Position: Chr18,
11.35 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: The mutation in the lah allele was identified as an A to C transversion at nucleotide 587 within exon 6. The mutation causes a tyrosine to serine change at amino acid position 196 affecting a potential phosphorylation site. (J:83118)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:33849
Montagutelli X et al.,
"Lanceolate hair (lah): a recessive mouse mutation with alopecia and abnormal hair."
J Invest Dermatol 1996 Jul;107(1):20-5
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All: |
3 reference(s)
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Analysis Tools
