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| Nomenclature |
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Symbol:
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Ay
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Name:
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nonagouti;
agouti yellow
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MGI ID: |
MGI:1856798 |
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Synonyms: |
Ay, A(y) |
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Gene:
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a
Location:
Chr2:154791402-155051012 bp, + strand
Genetic Position: Chr2,
76.83 cM
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Ay/a mouse
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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old mutant of the mouse fancy
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Other |
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Mutation details: The Ay mutation appears to be a DNA structural alteration that disrupts a gene, hnRNP associated with lethal yellow (Raly), 5' to the agouti locus and places the agouti locus under the control of the Raly promotor. A report of recombination between Ay and the a and ax alleles suggests that Ay was a pseudoallele of the a locus on the proximal side. However, cloning of the agouti locus and molecular analysis of a showed that the coding region of the three alleles is identical. (J:8877, J:12911, J:17512, J:18921)
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Inheritance: | |
Semidominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:12954
Dunn LC et al.,
"Studies on Spotting Patterns III. Interaction between Genes Affecting White Spotting and Those Affecting Color in the House Mouse."
Genetics 1937 Mar;22(2):307-18
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All: |
145 reference(s)
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Analysis Tools
