|
|
| Nomenclature |
|
Symbol:
|
Foxc1ch
|
|
Name:
|
forkhead box C1;
congenital hydrocephalus
|
|
MGI ID: |
MGI:1856705 |
|
Synonyms: |
ch, mf1ch |
|
Gene:
|
Foxc1
Location:
Chr13:31806691-31810643 bp, + strand
Genetic Position: Chr13,
13.52 cM
|
|
Foxc1ch/Foxc1ch
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Strain of Origin:
|
CBA x STOCK Tyrc f
|
|
Mutation
description |
|
Allele
Type: | |
Spontaneous |
|
Mutation: | |
Single point mutation |
| |
|
Mutation details: A transition point mutation at nucleotide 366 altered a C to a T in the coding region. This results in a stop codon in the sequences encoding the third helix of the WH domain, and the authors predict that a truncated protein would be generated lacking DNA binding activity. (J:48079)
|
|
Inheritance: | |
Recessive |
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:75733
Gruneberg H,
"Congenital hydrocephalus in the mouse, a case of spurious pleiotropism"
J Genet 1943;45(1):1-21
|
|
All: |
16 reference(s)
|
|
Analysis Tools
