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| Nomenclature |
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Symbol:
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Bicc1jcpk-bpk
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Name:
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bicaudal C homolog 1 (Drosophila);
polycystic kidney mutation of BALB/c origin
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MGI ID: |
MGI:1856693 |
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Synonyms: |
bpk, jcpk/bpk |
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Gene:
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Bicc1
Location:
Chr10:70922832-71159700 bp, - strand
Genetic Position: Chr10,
36.75 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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Mutation details: The mutation in the bpk mouse was identified as a 2 base pair insertion in exon 22. This mutation is predicted to extent the length of Transcript A by 129 amino acids. Transcript B would be unaffected since the stop codon in Transcript B occurs before the mutation. (J:82707)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Bicc1 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:13276
Nauta J et al.,
"Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease."
Pediatr Nephrol 1993 Apr;7(2):163-72
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All: |
13 reference(s)
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Analysis Tools
