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| Nomenclature |
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Symbol:
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Dtnbp1sdy
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Name:
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dystrobrevin binding protein 1;
sandy
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MGI ID: |
MGI:1856628 |
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Synonyms: |
Dys-, Dys KO, sdy, sdy- |
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Gene:
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Dtnbp1
Location:
Chr13:44922079-45002096 bp, - strand
Genetic Position: Chr13,
21.73 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Intragenic deletion |
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Mutation details: The mutation in the sandy mouse has been attributed to a deletion in the Dtnbp1 gene from intron 5 nucleotide 3701 to intron 7 nucleotide 12377. The deletion results in the loss of 52 amino acids from position 119-172 and abolishes expression of the protein. Western analysis did not detect protein in hippocampus tissue from homozygous mutant mice. (J:85123, J:169460)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Analysis Tools
