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| Nomenclature |
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Symbol:
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Pax6132-14Neu
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Name:
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paired box gene 6;
132-14, Neuherberg
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MGI ID: |
MGI:1856585 |
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Synonyms: |
Apyc, Cat4a, Cat4Apcat1-1 |
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Gene:
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Pax6
Location:
Chr2:105668896-105703160 bp, + strand
Genetic Position: Chr2,
55.31 cM
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Pax6132-14Neu/Pax6+ and Pax6132-14Neu/Pax6132-14Neu histological adult eye sections.
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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(102 x C3H)F1
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Mutation
description |
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Allele
Type: | |
Radiation induced |
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Mutation: | |
Single point mutation |
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Mutation details: Mice contain a T to A transversion at position 1099 that results in an amino acid substitution of isoleucine for phenylalanine at position 272 (F272I). (J:137541)
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Inheritance: | |
Semidominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Pax6 Mutation:
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33 strains or lines available |
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| References |
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Original: |
J:6686
Kratochvilova J,
"Dominant cataract mutations detected in offspring of gamma-irradiated male mice."
J Hered 1981 Sep-Oct;72(5):302-7
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All: |
6 reference(s)
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Analysis Tools
