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| Nomenclature |
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Symbol:
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Egfrwa2
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Name:
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epidermal growth factor receptor;
waved 2
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MGI ID: |
MGI:1856397 |
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Synonyms: |
wa2, wa-2, waved2 |
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Gene:
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Egfr
Location:
Chr11:16752203-16918158 bp, + strand
Genetic Position: Chr11,
9.41 cM, cytoband A1-A4
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Mammary gland histology of an Egfrwa2/Egfrwa2 mouse
Show the 3 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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STOCK ac
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: A T-to-G transversion mutation in the sequences encoding the tyrosine kinase domain is predicted to result in a substitution of a glycine for a highly conserved valine at position 743 in the third kinase subdomain. (J:16986)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Found by Keeler in an abnormal corpus callosum'' stock at the Bussey Institution.
Phenotypic Similarity to Human Syndrome: Aortic Valve Disease in homozygous mice in J:60750
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| References |
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Original: |
J:13052
Keeler CE,
"A second rexoid coat character in the house mouse."
J Hered 1935;26():189-191
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All: |
50 reference(s)
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Analysis Tools
