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| Nomenclature |
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Symbol:
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Pcdh15av-3J
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Name:
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protocadherin 15;
Ames waltzer 3 Jackson
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MGI ID: |
MGI:1856394 |
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Synonyms: |
av3J, Pcdh15av-3J |
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Gene:
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Pcdh15
Location:
Chr10:73099342-74646314 bp, + strand
Genetic Position: Chr10,
37.43 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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Mutation details: An insertion of a single A nucleotide after position 4521 in the coding region results in a frameshift and a premature stop codon. Any encoded protein is predicted to lack a cytoplasmic domain. (J:66738)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
These homozygotes, like Pcdh15av-J homozygotes, can swim, though with difficulty. They tend to circle while afloat (J:28688).
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| References |
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Original: |
J:28688
Cook S et al.,
"Re-mutation to Ames waltzer"
Mouse Genome 1993;91():554
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All: |
18 reference(s)
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Analysis Tools
