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| Nomenclature |
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Symbol:
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Faslgld
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Name:
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Fas ligand (TNF superfamily, member 6);
generalized lymphoproliferative disease
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MGI ID: |
MGI:1856384 |
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Synonyms: |
CD95-, FasL-, gld, Tnfsf6gld |
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Gene:
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Fasl
Location:
Chr1:161780691-161788495 bp, - strand
Genetic Position: Chr1,
69.95 cM
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control and Faslgld/Faslgld
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C3H/HeJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: A T-to-C transition point mutation near the 3' end of the coding sequence causes a replacement of a highly conserved phenylalanine with a leucine at position 273 in the extracellular region of the encoded protein. (J:17445)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:29572
Murphy ED et al.,
"Generalized lymphoproliferative disease (gld)"
Mouse News Lett 1982;67():20-1
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All: |
309 reference(s)
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Analysis Tools
