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| Nomenclature |
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Symbol:
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Btkxid
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Name:
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Bruton agammaglobulinemia tyrosine kinase;
X linked immune deficiency
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MGI ID: |
MGI:1856317 |
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Synonyms: |
xid |
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Gene:
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Btk
Location:
ChrX:134542336-134583570 bp, - strand
Genetic Position: ChrX,
56.18 cM
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: The C to T transition point mutation at position 219 is predicted to change amino acid 28 from an arginine to a cysteine in the encoded protein. (J:13209)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:6296
Berning AK et al.,
"Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice."
J Immunol 1980 Apr;124(4):1875-7
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All: |
135 reference(s)
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Analysis Tools
