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| Nomenclature |
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Symbol:
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Yaa
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Name:
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accelerated autoimmunity and lymphoproliferation transposition;
accelerated autoimmunity and lymphoproliferation
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MGI ID: |
MGI:1856277 |
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Synonyms: |
Tp(X;Y)1Ekw |
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Gene:
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Yaa
Location:
unknown
Genetic Position: ChrY,
Syntenic
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Mutation
origin |
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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A region of the X chromosome that includes Tlr7 and Prps2 is translocated to the Y chromosome. (J:111064, J:140028)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
In congenic C57BL/6 Yaa mice expression of Tlr7 is increased 2-fold.
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| References |
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Original: |
J:6235
Murphy ED et al.,
"A Y chromosome associated factor in strain BXSB producing accelerated autoimmunity and lymphoproliferation."
Arthritis Rheum 1979 Nov;22(11):1188-94
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All: |
63 reference(s)
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Analysis Tools
