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| Nomenclature |
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Symbol:
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KitW-44J
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Name:
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kit oncogene;
dominant spotting 44 Jackson
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MGI ID: |
MGI:1856247 |
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Gene:
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Kit
Location:
Chr5:75574916-75656722 bp, + strand
Genetic Position: Chr5,
39.55 cM
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Mutation
origin |
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Strain of Origin:
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C3H/HeJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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Mutation details: Southern hybridization analyses of genomic DNA using probes corresponding to two specific lengths of amino acids from c-kit suggests that this allele comprises a 4-5 kb insertion that disrupts c-kit. The level of c-kit mRNA in homozygotes is markedly reduced. (J:9374)
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Inheritance: | |
Semidominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:6571
Geissler EN et al.,
"Analysis of pleiotropism at the dominant white-spotting (W) locus of the house mouse: a description of ten new W alleles."
Genetics 1981 Feb;97(2):337-61
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All: |
3 reference(s)
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Analysis Tools
