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| Nomenclature |
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Symbol:
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Atp7btx-J
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Name:
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ATPase, Cu++ transporting, beta polypeptide;
toxic milk Jackson
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MGI ID: |
MGI:1856221 |
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Gene:
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Atp7b
Location:
Chr8:21992785-22060305 bp, - strand
Genetic Position: Chr8,
10.78 cM
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Mutation
origin |
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Strain of Origin:
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C3H/HeJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: The mutation comprises a G to A base substitution at position 2135 in exon 8 of the gene. This is predicted to result in a Gly712Asp missense mutation in the second putative membrane-spanning domain of the encoded protein. (J:71896)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
Tests at the University of Massachusetts proved its allelism to the original toxic milk mutation (J:28232).
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| References |
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Original: |
J:28232
Sweet HO et al.,
"Toxic milk-J (tx<J>)"
Mouse News Lett 1989;84():89
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All: |
8 reference(s)
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Analysis Tools
