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| Nomenclature |
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Symbol:
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Lbric-J
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Name:
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lamin B receptor;
ichthyosis Jackson
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MGI ID: |
MGI:1856064 |
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Synonyms: |
icJ |
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Gene:
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Lbr
Location:
Chr1:181815316-181842401 bp, - strand
Genetic Position: Chr1,
84.89 cM
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Insertion |
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Mutation details: This phenotypic mutant was found to be allelic to ic by complementation testing. The mutation in the Lbric-J mouse was identified as 2 bp insertion at position 1088. This insertion results in a frame shift, changing amino acids 365-385, and creates a premature stop codon at amino acid position 386. (J:80915)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:24755
Eicher EM,
"Spontaneous mutations - streaker (nu<str>) and ichthyosis (ic<J>)"
Mouse News Lett 1976;54():40
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All: |
6 reference(s)
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Analysis Tools
