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| Nomenclature |
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Symbol:
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Tyrp1b
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Name:
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tyrosinase-related protein 1;
brown
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MGI ID: |
MGI:1855960 |
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Synonyms: |
b |
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Gene:
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Tyrp1
Location:
Chr4:80834123-80851719 bp, + strand
Genetic Position: Chr4,
37.89 cM
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a/a Tyrp1b/Tyrp1b
Show the 5 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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old mutant of the mouse fancy
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: A G-to-A transition point mutation at position 329 was shown by revertant analysis to be responsible for the mutant phenotype seen in the brown mutant. This mutation is predicted to change a cysteine residue to a tyrosine in the encoded protein. Three other point mutations in the brown sequence were identified, but do not contribute to the mutant phenotype. (J:44435)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Analysis Tools
