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| Nomenclature |
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Symbol:
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Ahvy
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Name:
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nonagouti;
hypervariable yellow
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MGI ID: |
MGI:1855945 |
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Gene:
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a
Location:
Chr2:154791402-155051012 bp, + strand
Genetic Position: Chr2,
76.83 cM
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Mutation
origin |
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Strain of Origin:
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C3H/HeJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Transposon insertion |
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Mutation details: Sequencing of 5' RACE and genomic PCR products revealed that this allele
resulted from the integration of an intracisternal A particle (IAP) in an antisense orientation within the 5'untranslated region of exon 1C. Methylation assay results indciate that the agouti and yellow mosaic phenotype characteristic of this allele is due to differential epigenetic methylation of the IAP. (J:31145, J:79708)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:24247
Siracusa LD et al.,
"Hypervariable yellow (Ahvy), a new murine agouti mutation: Ahvy displays the largest variation in coat color phenotypes of all known agouti alleles."
J Hered 1995 Mar-Apr;86(2):121-8
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All: |
4 reference(s)
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Analysis Tools
