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GO Annotations Graph
 Symbol
Name
ID
Notch2
notch 2
MGI:97364

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005509calcium ion bindingIEAJ:72247
Molecular FunctionGO:0019899enzyme bindingIPIJ:183220
Molecular FunctionGO:0051059NF-kappaB bindingIPIJ:140561
Molecular FunctionGO:0005515protein bindingIPIJ:40289
Molecular FunctionGO:0005515protein bindingIPIJ:58381
Molecular FunctionGO:0005515protein bindingIPIJ:115539
Cellular ComponentGO:0005623cellIGIJ:123631
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005929ciliumIDAJ:173367
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneICJ:58381
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0016020membraneISOJ:164563
Cellular ComponentGO:0005634nucleusIDAJ:115539
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0060413atrial septum morphogenesisISOJ:164563
Biological ProcessGO:0046849bone remodelingISOJ:164563
Biological ProcessGO:0007050cell cycle arrestISOJ:164563
Biological ProcessGO:0030154cell differentiationIEAJ:60000
Biological ProcessGO:0030154cell differentiationIEAJ:72247
Biological ProcessGO:0001709cell fate determinationTASJ:115539
Biological ProcessGO:0001709cell fate determinationISOJ:155856
Biological ProcessGO:0016049cell growthISOJ:164563
Biological ProcessGO:0061073ciliary body morphogenesisIMPJ:197419
Biological ProcessGO:0042742defense response to bacteriumIMPJ:208234
Biological ProcessGO:0007368determination of left/right symmetryIMPJ:83358
Biological ProcessGO:0030326embryonic limb morphogenesisIGIJ:103603
Biological ProcessGO:0001947heart loopingIGIJ:83358
Biological ProcessGO:0006959humoral immune responseIGIJ:123631
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:120082
Biological ProcessGO:0002437inflammatory response to antigenic stimulusIGIJ:123631
Biological ProcessGO:0072602interleukin-4 secretionIGIJ:123631
Biological ProcessGO:0070986left/right axis specificationIGIJ:83358
Biological ProcessGO:0002011morphogenesis of an epithelial sheetIMPJ:74574
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:60000
Biological ProcessGO:0007275multicellular organismal developmentIEAJ:72247
Biological ProcessGO:0043011myeloid dendritic cell differentiationIMPJ:208234
Biological ProcessGO:0008285negative regulation of cell proliferationISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:197419
Biological ProcessGO:0007219Notch signaling pathwayICJ:58381
Biological ProcessGO:0007219Notch signaling pathwayTASJ:97734
Biological ProcessGO:0009887organ morphogenesisTASJ:115539
Biological ProcessGO:0060674placenta blood vessel developmentIMPJ:120082
Biological ProcessGO:0001890placenta developmentIMPJ:120082
Biological ProcessGO:0043065positive regulation of apoptotic processIGIJ:103603
Biological ProcessGO:0030513positive regulation of BMP signaling pathwayIMPJ:197419
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:197419
Biological ProcessGO:0045672positive regulation of osteoclast differentiationIDAJ:140561
Biological ProcessGO:0046579positive regulation of Ras protein signal transductionISOJ:164563
Biological ProcessGO:0003184pulmonary valve morphogenesisISOJ:164563
Biological ProcessGO:0050793regulation of developmental processIEAJ:72247
Biological ProcessGO:0006355regulation of transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0006351transcription, DNA-templatedIEAJ:60000
Biological ProcessGO:0042060wound healingIDAJ:115539

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory