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GO Annotations Graph
 Symbol
Name
ID
Nedd4
neural precursor cell expressed, developmentally down-regulated 4
MGI:97297

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0031698beta-2 adrenergic receptor bindingISOJ:164563
Molecular FunctionGO:0016874ligase activityIEAJ:60000
Molecular FunctionGO:0050815phosphoserine bindingIDAJ:140385
Molecular FunctionGO:0050816phosphothreonine bindingIDAJ:140385
Molecular FunctionGO:0070064proline-rich region bindingIPIJ:75315
Molecular FunctionGO:0070064proline-rich region bindingIPIJ:140926
Molecular FunctionGO:0070064proline-rich region bindingISOJ:164563
Molecular FunctionGO:0005515protein bindingIPIJ:56881
Molecular FunctionGO:0005515protein bindingIPIJ:65663
Molecular FunctionGO:0005515protein bindingIPIJ:65663
Molecular FunctionGO:0005515protein bindingIPIJ:122283
Molecular FunctionGO:0005515protein bindingIPIJ:122283
Molecular FunctionGO:0005515protein bindingIPIJ:159070
Molecular FunctionGO:0005515protein bindingIPIJ:164713
Molecular FunctionGO:0005515protein bindingIPIJ:164745
Molecular FunctionGO:0005515protein bindingIPIJ:178643
Molecular FunctionGO:0008022protein C-terminus bindingISOJ:155856
Molecular FunctionGO:0019904protein domain specific bindingISOJ:164563
Molecular FunctionGO:0070063RNA polymerase bindingISOJ:164563
Molecular FunctionGO:0019871sodium channel inhibitor activityIDAJ:54531
Molecular FunctionGO:0019871sodium channel inhibitor activityISOJ:164563
Molecular FunctionGO:0043130ubiquitin bindingISOJ:164563
Molecular FunctionGO:0004842ubiquitin-protein ligase activityIDAJ:41090
Molecular FunctionGO:0004842ubiquitin-protein ligase activityISOJ:155856
Molecular FunctionGO:0004842ubiquitin-protein ligase activityISOJ:164563
Molecular FunctionGO:0004842ubiquitin-protein ligase activityIDAJ:164713
Cellular ComponentGO:0005938cell cortexISOJ:164563
Cellular ComponentGO:0000785chromatinISOJ:164563
Cellular ComponentGO:0005737cytoplasmIDAJ:89097
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0005829cytosolIDAJ:41090
Cellular ComponentGO:0005829cytosolIDAJ:164173
Cellular ComponentGO:0005794Golgi apparatusISOJ:164563
Cellular ComponentGO:0016020membraneIDAJ:89097
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0005902microvillusISOJ:155856
Cellular ComponentGO:0005634nucleusIBAJ:161428
Cellular ComponentGO:0048471perinuclear region of cytoplasmISOJ:164563
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0000151ubiquitin ligase complexIPIJ:65663
Biological ProcessGO:0002250adaptive immune responseIMPJ:143560
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:159895
Biological ProcessGO:0048514blood vessel morphogenesisIGIJ:159895
Biological ProcessGO:0034644cellular response to UVISOJ:164563
Biological ProcessGO:0044111development involved in symbiotic interactionISOJ:164563
Biological ProcessGO:0003197endocardial cushion developmentIMPJ:159895
Biological ProcessGO:0003197endocardial cushion developmentIGIJ:159895
Biological ProcessGO:0042921glucocorticoid receptor signaling pathwayISOJ:164563
Biological ProcessGO:0007041lysosomal transportISOJ:164563
Biological ProcessGO:0010766negative regulation of sodium ion transportIDAJ:54531
Biological ProcessGO:0010766negative regulation of sodium ion transportISOJ:164563
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:159895
Biological ProcessGO:0010768negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damageISOJ:164563
Biological ProcessGO:0030948negative regulation of vascular endothelial growth factor receptor signaling pathwayIDAJ:159070
Biological ProcessGO:0007399nervous system developmentIEAJ:60000
Biological ProcessGO:0007528neuromuscular junction developmentIMPJ:149227
Biological ProcessGO:0003151outflow tract morphogenesisIMPJ:159895
Biological ProcessGO:0003151outflow tract morphogenesisIGIJ:159895
Biological ProcessGO:0046824positive regulation of nucleocytoplasmic transportISOJ:164563
Biological ProcessGO:0014068positive regulation of phosphatidylinositol 3-kinase signalingISOJ:164563
Biological ProcessGO:0045732positive regulation of protein catabolic processISOJ:73065
Biological ProcessGO:0045732positive regulation of protein catabolic processIDAJ:75315
Biological ProcessGO:0050847progesterone receptor signaling pathwayISOJ:164563
Biological ProcessGO:0070534protein K63-linked ubiquitinationISOJ:155856
Biological ProcessGO:0006513protein monoubiquitinationIDAJ:178643
Biological ProcessGO:0006622protein targeting to lysosomeISOJ:164563
Biological ProcessGO:0016567protein ubiquitinationIDAJ:41090
Biological ProcessGO:0016567protein ubiquitinationISOJ:164563
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processIMPJ:143560
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processIBAJ:161428
Biological ProcessGO:0042787protein ubiquitination involved in ubiquitin-dependent protein catabolic processISOJ:164563
Biological ProcessGO:0032801receptor catabolic processISOJ:164563
Biological ProcessGO:0031623receptor internalizationISOJ:164563
Biological ProcessGO:0048814regulation of dendrite morphogenesisISOJ:155856
Biological ProcessGO:0048814regulation of dendrite morphogenesisIMPJ:164745
Biological ProcessGO:0034765regulation of ion transmembrane transportISOJ:164563
Biological ProcessGO:0042391regulation of membrane potentialISOJ:164563
Biological ProcessGO:1901016regulation of potassium ion transmembrane transporter activityISOJ:164563
Biological ProcessGO:0050807regulation of synapse organizationIMPJ:149227
Biological ProcessGO:0042110T cell activationIMPJ:143560
Biological ProcessGO:0019089transmission of virusISOJ:164563
Biological ProcessGO:0043162ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathwayISOJ:164563

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory