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GO Annotations Graph
 Symbol
Name
ID
Slc6a4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
MGI:96285

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0051015actin filament bindingISOJ:155856
Molecular FunctionGO:0019811cocaine bindingISOJ:155856
Molecular FunctionGO:0008504monoamine transmembrane transporter activityISOJ:100021
Molecular FunctionGO:0017022myosin bindingISOJ:155856
Molecular FunctionGO:0005328neurotransmitter:sodium symporter activityIEAJ:72247
Molecular FunctionGO:0050998nitric-oxide synthase bindingIPIJ:121594
Molecular FunctionGO:0005515protein bindingIPIJ:121594
Molecular FunctionGO:0005515protein bindingIPIJ:121594
Molecular FunctionGO:0042803protein homodimerization activityISOJ:155856
Molecular FunctionGO:0017137Rab GTPase bindingISOJ:164563
Molecular FunctionGO:0015222serotonin transmembrane transporter activityISOJ:155856
Molecular FunctionGO:0015222serotonin transmembrane transporter activityISOJ:164563
Molecular FunctionGO:0005335serotonin:sodium symporter activityISOJ:164563
Molecular FunctionGO:0015293symporter activityIEAJ:60000
Molecular FunctionGO:0017075syntaxin-1 bindingISOJ:155856
Cellular ComponentGO:0005829cytosolISOJ:164563
Cellular ComponentGO:0012505endomembrane systemISOJ:155856
Cellular ComponentGO:0012505endomembrane systemISOJ:164563
Cellular ComponentGO:0005768endosomeIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0045121membrane raftISOJ:155856
Cellular ComponentGO:0045121membrane raftISOJ:164563
Cellular ComponentGO:0043005neuron projectionISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:155856
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Biological ProcessGO:0048854brain morphogenesisIMPJ:144937
Biological ProcessGO:0071321cellular response to cGMPISOJ:155856
Biological ProcessGO:0071310cellular response to organic substanceIDAJ:138764
Biological ProcessGO:0007623circadian rhythmISOJ:155856
Biological ProcessGO:0007613memoryISOJ:155856
Biological ProcessGO:0015844monoamine transportISOJ:100021
Biological ProcessGO:0021941negative regulation of cerebellar granule cell precursor proliferationISOJ:155856
Biological ProcessGO:0045665negative regulation of neuron differentiationISOJ:155856
Biological ProcessGO:0046621negative regulation of organ growthIMPJ:144937
Biological ProcessGO:0032227negative regulation of synaptic transmission, dopaminergicISOJ:155856
Biological ProcessGO:0006836neurotransmitter transportIEAJ:60000
Biological ProcessGO:0006836neurotransmitter transportIEAJ:72247
Biological ProcessGO:0045787positive regulation of cell cycleIMPJ:162980
Biological ProcessGO:0010628positive regulation of gene expressionIMPJ:162980
Biological ProcessGO:0051260protein homooligomerizationISOJ:155856
Biological ProcessGO:0051259protein oligomerizationISOJ:155856
Biological ProcessGO:0009636response to toxic substanceISOJ:164563
Biological ProcessGO:0006837serotonin transportISOJ:155856
Biological ProcessGO:0006837serotonin transportIMPJ:162980
Biological ProcessGO:0006837serotonin transportISOJ:164563
Biological ProcessGO:0051610serotonin uptakeIMPJ:76020
Biological ProcessGO:0051610serotonin uptakeIDAJ:121594
Biological ProcessGO:0051610serotonin uptakeISOJ:155856
Biological ProcessGO:0051610serotonin uptakeISOJ:164563
Biological ProcessGO:0035176social behaviorIGIJ:144937
Biological ProcessGO:0035725sodium ion transmembrane transportISOJ:164563
Biological ProcessGO:0042713sperm ejaculationISOJ:155856
Biological ProcessGO:0021794thalamus developmentISOJ:164563
Biological ProcessGO:0006810transportIEAJ:60000
Biological ProcessGO:0042310vasoconstrictionISOJ:155856

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory