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GO Annotations Graph
 Symbol
Name
ID
Fgfr3
fibroblast growth factor receptor 3
MGI:95524

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:73065
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:155856
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:164563
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityIDAJ:88289
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:155856
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:76351
Molecular FunctionGO:0005515protein bindingIPIJ:110570
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0009898cytoplasmic side of plasma membraneIDAJ:88289
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0005783endoplasmic reticulumIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0005764lysosomeIDAJ:88289
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0048471perinuclear region of cytoplasmIDAJ:88289
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0061144alveolar secondary septum developmentIGIJ:50677
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0060385axonogenesis involved in innervationIMPJ:122378
Biological ProcessGO:0070977bone maturationIMPJ:161199
Biological ProcessGO:0060349bone morphogenesisIMPJ:151194
Biological ProcessGO:0051216cartilage developmentIMPJ:99916
Biological ProcessGO:0030154cell differentiationIMPJ:122378
Biological ProcessGO:0007267cell-cell signalingISOJ:155856
Biological ProcessGO:0022010central nervous system myelinationIMPJ:81919
Biological ProcessGO:0090102cochlea developmentIMPJ:122378
Biological ProcessGO:0048546digestive tract morphogenesisIMPJ:151194
Biological ProcessGO:0072148epithelial cell fate commitmentIMPJ:151194
Biological ProcessGO:1902178fibroblast growth factor receptor apoptotic signaling pathwayISOJ:164563
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIDAJ:88289
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:99916
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:153198
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0030900forebrain developmentIMPJ:96234
Biological ProcessGO:0048839inner ear developmentIMPJ:117235
Biological ProcessGO:0060113inner ear receptor cell differentiationIMPJ:117235
Biological ProcessGO:0060113inner ear receptor cell differentiationIGIJ:122387
Biological ProcessGO:0070307lens fiber cell developmentIGIJ:136711
Biological ProcessGO:0002089lens morphogenesis in camera-type eyeIMPJ:68695
Biological ProcessGO:0000165MAPK cascadeIDAJ:88289
Biological ProcessGO:0002009morphogenesis of an epitheliumIMPJ:117235
Biological ProcessGO:0048712negative regulation of astrocyte differentiationIMPJ:81919
Biological ProcessGO:0008285negative regulation of cell proliferationIMPJ:96234
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:136711
Biological ProcessGO:0048640negative regulation of developmental growthIMPJ:161199
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationIMPJ:68695
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationISOJ:73065
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationIMPJ:121934
Biological ProcessGO:0045839negative regulation of mitosisIGIJ:136711
Biological ProcessGO:0045879negative regulation of smoothened signaling pathwayIMPJ:50292
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:50292
Biological ProcessGO:0014003oligodendrocyte developmentIMPJ:81919
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationIDAJ:88289
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0090263positive regulation of canonical Wnt signaling pathwayIMPJ:151194
Biological ProcessGO:0045597positive regulation of cell differentiationIMPJ:79996
Biological ProcessGO:0045597positive regulation of cell differentiationIMPJ:117235
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:73065
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:153198
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:155856
Biological ProcessGO:0001938positive regulation of endothelial cell proliferationIMPJ:111764
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeISOJ:164563
Biological ProcessGO:0043410positive regulation of MAPK cascadeIMPJ:68695
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:73065
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:73065
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0090080positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathwayIGIJ:153198
Biological ProcessGO:0043525positive regulation of neuron apoptotic processIMPJ:96234
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationIDAJ:88289
Biological ProcessGO:0043552positive regulation of phosphatidylinositol 3-kinase activityISOJ:164563
Biological ProcessGO:0010518positive regulation of phospholipase activityISOJ:164563
Biological ProcessGO:0031398positive regulation of protein ubiquitinationIDAJ:88289
Biological ProcessGO:0042511positive regulation of tyrosine phosphorylation of Stat1 proteinISOJ:164563
Biological ProcessGO:0042517positive regulation of tyrosine phosphorylation of Stat3 proteinISOJ:164563
Biological ProcessGO:0036342post-anal tail morphogenesisIMPJ:161199
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0048678response to axon injuryIMPJ:104421
Biological ProcessGO:0001501skeletal system developmentIEAJ:72247
Biological ProcessGO:0035019somatic stem cell maintenanceIMPJ:151194
Biological ProcessGO:0021762substantia nigra developmentIMPJ:117417

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory