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GO Annotations Graph
 Symbol
Name
ID
Fgfr2
fibroblast growth factor receptor 2
MGI:95523

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Wed Jul 23 12:17:05 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0017134fibroblast growth factor bindingIDAJ:46380
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:73065
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:73065
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:155856
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:73065
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:155856
Molecular FunctionGO:0008201heparin bindingIEAJ:60000
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:13170
Molecular FunctionGO:0005515protein bindingIPIJ:110570
Molecular FunctionGO:0005515protein bindingIPIJ:174064
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:60000
Molecular FunctionGO:0004713protein tyrosine kinase activityIEAJ:72247
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Cellular ComponentGO:0005623cellIMPJ:126496
Cellular ComponentGO:0005938cell cortexISOJ:164563
Cellular ComponentGO:0009986cell surfaceISOJ:155856
Cellular ComponentGO:0009986cell surfaceISOJ:164563
Cellular ComponentGO:0005737cytoplasmISOJ:155856
Cellular ComponentGO:0005737cytoplasmISOJ:164563
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0060076excitatory synapseIMPJ:159839
Cellular ComponentGO:0031012colocalizes_with
extracellular matrix
ISOJ:164563
Cellular ComponentGO:0005576extracellular regionTASJ:76640
Cellular ComponentGO:0005794Golgi apparatusIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0005887integral component of plasma membraneISOJ:164563
Cellular ComponentGO:0043231intracellular membrane-bounded organelleISOJ:164563
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005634nucleusIDAJ:92065
Cellular ComponentGO:0005634nucleusIDAJ:99790
Cellular ComponentGO:0005634nucleusISOJ:155856
Cellular ComponentGO:0005634nucleusISOJ:164563
Cellular ComponentGO:0005886plasma membraneIEAJ:60000
Biological ProcessGO:0001525angiogenesisIGIJ:109722
Biological ProcessGO:0006915apoptotic processIEAJ:60000
Biological ProcessGO:0007409axonogenesisIMPJ:127453
Biological ProcessGO:0060348bone developmentIMPJ:114396
Biological ProcessGO:0030282bone mineralizationIMPJ:90391
Biological ProcessGO:0060349bone morphogenesisIMPJ:58117
Biological ProcessGO:0060667branch elongation involved in salivary gland morphogenesisIMPJ:119849
Biological ProcessGO:0060667branch elongation involved in salivary gland morphogenesisIGIJ:119849
Biological ProcessGO:0060670branching involved in labyrinthine layer morphogenesisIMPJ:46380
Biological ProcessGO:0060442branching involved in prostate gland morphogenesisIMPJ:82767
Biological ProcessGO:0060442branching involved in prostate gland morphogenesisIMPJ:119911
Biological ProcessGO:0060445branching involved in salivary gland morphogenesisIMPJ:74539
Biological ProcessGO:0048755branching morphogenesis of a nerveIMPJ:127453
Biological ProcessGO:0060449bud elongation involved in lung branchingIMPJ:114396
Biological ProcessGO:0045165cell fate commitmentIDAJ:94813
Biological ProcessGO:0007267cell-cell signalingIMPJ:90909
Biological ProcessGO:0060365coronal suture morphogenesisIMPJ:149465
Biological ProcessGO:0048565digestive tract developmentIMPJ:92361
Biological ProcessGO:0048701embryonic cranial skeleton morphogenesisISOJ:164563
Biological ProcessGO:0048557embryonic digestive tract morphogenesisIMPJ:124918
Biological ProcessGO:0048557embryonic digestive tract morphogenesisIMPJ:175282
Biological ProcessGO:0048568embryonic organ developmentIMPJ:46380
Biological ProcessGO:0048562embryonic organ morphogenesisIMPJ:98380
Biological ProcessGO:0009880embryonic pattern specificationIMPJ:124918
Biological ProcessGO:0061031endodermal digestive tract morphogenesisIMPJ:175282
Biological ProcessGO:0048730epidermis morphogenesisIMPJ:85732
Biological ProcessGO:0030855epithelial cell differentiationIMPJ:124918
Biological ProcessGO:0050673epithelial cell proliferationIMPJ:98380
Biological ProcessGO:0050673epithelial cell proliferationIMPJ:119453
Biological ProcessGO:0060664epithelial cell proliferation involved in salivary gland morphogenesisIGIJ:119849
Biological ProcessGO:0060664epithelial cell proliferation involved in salivary gland morphogenesisIMPJ:119849
Biological ProcessGO:0001837epithelial to mesenchymal transitionISOJ:155856
Biological ProcessGO:0060441epithelial tube branching involved in lung morphogenesisIMPJ:202949
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIMPJ:46380
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:95803
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:109722
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:119849
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:119935
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:153198
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:155856
Biological ProcessGO:0035603fibroblast growth factor receptor signaling pathway involved in hemopoiesisIMPJ:168171
Biological ProcessGO:0060595fibroblast growth factor receptor signaling pathway involved in mammary gland specificationIMPJ:109476
Biological ProcessGO:0035602fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrowIMPJ:168171
Biological ProcessGO:0035607fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentIMPJ:159839
Biological ProcessGO:0035604fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrowIMPJ:168171
Biological ProcessGO:0022612gland morphogenesisIMPJ:119935
Biological ProcessGO:0031069hair follicle morphogenesisIMPJ:85732
Biological ProcessGO:0001701in utero embryonic developmentIMPJ:46380
Biological ProcessGO:0001701in utero embryonic developmentIGIJ:123685
Biological ProcessGO:0042472inner ear morphogenesisIMPJ:72516
Biological ProcessGO:0032808lacrimal gland developmentIMPJ:62162
Biological ProcessGO:0060601lateral sprouting from an epitheliumIMPJ:82767
Biological ProcessGO:0070307lens fiber cell developmentIGIJ:136711
Biological ProcessGO:0070307lens fiber cell developmentIMPJ:189960
Biological ProcessGO:0060174limb bud formationIMPJ:46380
Biological ProcessGO:0060174limb bud formationIMPJ:58117
Biological ProcessGO:0048286lung alveolus developmentIMPJ:114396
Biological ProcessGO:0048286lung alveolus developmentIGIJ:114396
Biological ProcessGO:0030324lung developmentIMPJ:58117
Biological ProcessGO:0030324lung developmentIGIJ:107406
Biological ProcessGO:0060463lung lobe morphogenesisIMPJ:114396
Biological ProcessGO:0060484lung-associated mesenchyme developmentIMPJ:114396
Biological ProcessGO:0060484lung-associated mesenchyme developmentIGIJ:137691
Biological ProcessGO:0060615mammary gland bud formationIMPJ:73434
Biological ProcessGO:0003149membranous septum morphogenesisIMPJ:111148
Biological ProcessGO:0048762mesenchymal cell differentiationIGIJ:107078
Biological ProcessGO:0060915mesenchymal cell differentiation involved in lung developmentIGIJ:114396
Biological ProcessGO:0060916mesenchymal cell proliferation involved in lung developmentIMPJ:114396
Biological ProcessGO:0030901midbrain developmentIGIJ:123685
Biological ProcessGO:0016331morphogenesis of embryonic epitheliumIMPJ:98380
Biological ProcessGO:0035264multicellular organism growthIMPJ:114396
Biological ProcessGO:0008285negative regulation of cell proliferationIGIJ:136711
Biological ProcessGO:0050680negative regulation of epithelial cell proliferationISOJ:155856
Biological ProcessGO:0045839negative regulation of mitosisIGIJ:136711
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:114396
Biological ProcessGO:0007528neuromuscular junction developmentIMPJ:126496
Biological ProcessGO:0042476odontogenesisIMPJ:127453
Biological ProcessGO:0021769orbitofrontal cortex developmentIMPJ:159839
Biological ProcessGO:0035265organ growthIMPJ:124918
Biological ProcessGO:0009887organ morphogenesisIMPJ:82767
Biological ProcessGO:0030916otic vesicle formationIMPJ:46380
Biological ProcessGO:0003148outflow tract septum morphogenesisIMPJ:111148
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0090263positive regulation of canonical Wnt signaling pathwayIMPJ:109476
Biological ProcessGO:0090263positive regulation of canonical Wnt signaling pathwayIGIJ:137691
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationIGIJ:95803
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationIGIJ:95803
Biological ProcessGO:0045787positive regulation of cell cycleIMPJ:159839
Biological ProcessGO:0051781positive regulation of cell divisionIMPJ:85732
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:73065
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:85732
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:90909
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:109722
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:153198
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:159839
Biological ProcessGO:0050679positive regulation of epithelial cell proliferationIGIJ:119849
Biological ProcessGO:0060501positive regulation of epithelial cell proliferation involved in lung morphogenesisIMPJ:114396
Biological ProcessGO:0070374positive regulation of ERK1 and ERK2 cascadeIGIJ:119935
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIGIJ:107406
Biological ProcessGO:0010518positive regulation of phospholipase activityISOJ:164563
Biological ProcessGO:0048661positive regulation of smooth muscle cell proliferationISOJ:155856
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:114396
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterIMPJ:159839
Biological ProcessGO:0030177positive regulation of Wnt signaling pathwayIMPJ:114396
Biological ProcessGO:0009791post-embryonic developmentIMPJ:114396
Biological ProcessGO:0060527prostate epithelial cord arborization involved in prostate glandular acinus morphogenesisIMPJ:119911
Biological ProcessGO:0060523prostate epithelial cord elongationIMPJ:119911
Biological ProcessGO:0060512prostate gland morphogenesisIMPJ:131096
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0021860pyramidal neuron developmentIMPJ:159839
Biological ProcessGO:0060687regulation of branching involved in prostate gland morphogenesisIMPJ:119935
Biological ProcessGO:0010453regulation of cell fate commitmentIMPJ:114396
Biological ProcessGO:0042127regulation of cell proliferationIMPJ:90391
Biological ProcessGO:0050678regulation of epithelial cell proliferationIMPJ:119911
Biological ProcessGO:0050678regulation of epithelial cell proliferationIMPJ:131096
Biological ProcessGO:0070372regulation of ERK1 and ERK2 cascadeIMPJ:114396
Biological ProcessGO:0040036regulation of fibroblast growth factor receptor signaling pathwayIMPJ:114396
Biological ProcessGO:0060688regulation of morphogenesis of a branching structureIMPJ:119935
Biological ProcessGO:0040014regulation of multicellular organism growthIMPJ:46380
Biological ProcessGO:0051150regulation of smooth muscle cell differentiationIMPJ:114396
Biological ProcessGO:0008589regulation of smoothened signaling pathwayIMPJ:124918
Biological ProcessGO:0048608reproductive structure developmentIMPJ:82767
Biological ProcessGO:0060529squamous basal epithelial stem cell differentiation involved in prostate gland acinus developmentIMPJ:119911
Biological ProcessGO:0048489synaptic vesicle transportIMPJ:126496
Biological ProcessGO:0001657ureteric bud developmentIGIJ:107078
Biological ProcessGO:0060979vasculogenesis involved in coronary vascular morphogenesisTASJ:169941
Biological ProcessGO:0055010ventricular cardiac muscle tissue morphogenesisIMPJ:111148
Biological ProcessGO:0021847ventricular zone neuroblast divisionIMPJ:159839

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory