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GO Annotations Graph
 Symbol
Name
ID
Fgfr1
fibroblast growth factor receptor 1
MGI:95522

GO annotations  (Text View)    (Tabular View)

A table of the annotations represented in this image is provided below.
  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
  • Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
  • Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
  • Graph generated Fri Jan 17 13:56:29 2014.

CategoryGO IDClassification TermEvidenceReference
Molecular FunctionGO:0005524ATP bindingIEAJ:60000
Molecular FunctionGO:0005524ATP bindingIEAJ:72247
Molecular FunctionGO:0050839cell adhesion molecule bindingISOJ:155856
Molecular FunctionGO:0017134fibroblast growth factor bindingIPIJ:117479
Molecular FunctionGO:0017134fibroblast growth factor bindingISOJ:164563
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityIDAJ:31506
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:73065
Molecular FunctionGO:0005007fibroblast growth factor-activated receptor activityISOJ:164563
Molecular FunctionGO:0001948glycoprotein bindingISOJ:155856
Molecular FunctionGO:0008201heparin bindingISOJ:164563
Molecular FunctionGO:0042802identical protein bindingISOJ:164563
Molecular FunctionGO:0016301kinase activityIEAJ:60000
Molecular FunctionGO:0000166nucleotide bindingIEAJ:60000
Molecular FunctionGO:0005515protein bindingIPIJ:117479
Molecular FunctionGO:0005515protein bindingIPIJ:200439
Molecular FunctionGO:0032403protein complex bindingISOJ:155856
Molecular FunctionGO:0042803protein homodimerization activityISOJ:164563
Molecular FunctionGO:0004672protein kinase activityIEAJ:72247
Molecular FunctionGO:0004713protein tyrosine kinase activityISOJ:164563
Molecular FunctionGO:0016740transferase activityIEAJ:60000
Molecular FunctionGO:0016772transferase activity, transferring phosphorus-containing groupsIEAJ:72247
Molecular FunctionGO:0004714transmembrane receptor protein tyrosine kinase activityIEAJ:72245
Cellular ComponentGO:0005737cytoplasmIEAJ:60000
Cellular ComponentGO:0031410cytoplasmic vesicleIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:60000
Cellular ComponentGO:0016021integral component of membraneIEAJ:72247
Cellular ComponentGO:0016020membraneIEAJ:60000
Cellular ComponentGO:0005634nucleusIEAJ:60000
Cellular ComponentGO:0005886plasma membraneISOJ:164563
Cellular ComponentGO:0043235receptor complexISOJ:194542
Biological ProcessGO:0001525angiogenesisIGIJ:109722
Biological ProcessGO:0060117auditory receptor cell developmentIMPJ:95895
Biological ProcessGO:0048514blood vessel morphogenesisIMPJ:103237
Biological ProcessGO:0007420brain developmentIMPJ:83004
Biological ProcessGO:0060445branching involved in salivary gland morphogenesisIMPJ:79832
Biological ProcessGO:0060445branching involved in salivary gland morphogenesisIMPJ:140258
Biological ProcessGO:0048469cell maturationIMPJ:103237
Biological ProcessGO:0021954central nervous system neuron developmentISOJ:155856
Biological ProcessGO:0002062chondrocyte differentiationIGIJ:122952
Biological ProcessGO:0030326embryonic limb morphogenesisIMPJ:102949
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:31506
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIDAJ:31506
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayISOJ:73065
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:95803
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:109722
Biological ProcessGO:0008543fibroblast growth factor receptor signaling pathwayIGIJ:153198
Biological ProcessGO:0035607fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex developmentIMPJ:159839
Biological ProcessGO:0048699generation of neuronsIMPJ:105216
Biological ProcessGO:0001701in utero embryonic developmentIGIJ:123685
Biological ProcessGO:0042472inner ear morphogenesisIMPJ:78879
Biological ProcessGO:0060173limb developmentIEAJ:72247
Biological ProcessGO:0030324lung developmentIMPJ:94299
Biological ProcessGO:0030324lung developmentIGIJ:107406
Biological ProcessGO:0060484lung-associated mesenchyme developmentIGIJ:137691
Biological ProcessGO:0048762mesenchymal cell differentiationIGIJ:107078
Biological ProcessGO:0030901midbrain developmentIMPJ:123685
Biological ProcessGO:0030901midbrain developmentIGIJ:123685
Biological ProcessGO:0042474middle ear morphogenesisIMPJ:95895
Biological ProcessGO:0021837motogenic signaling involved in postnatal olfactory bulb interneuron migrationISOJ:155856
Biological ProcessGO:0010629negative regulation of gene expressionIMPJ:132412
Biological ProcessGO:0045668negative regulation of osteoblast differentiationISOJ:155856
Biological ProcessGO:0000122negative regulation of transcription from RNA polymerase II promoterIMPJ:159839
Biological ProcessGO:0031175neuron projection developmentISOJ:155856
Biological ProcessGO:0021769orbitofrontal cortex developmentIMPJ:159839
Biological ProcessGO:0001759organ inductionIMPJ:94299
Biological ProcessGO:0042473outer ear morphogenesisIMPJ:95895
Biological ProcessGO:0048339paraxial mesoderm developmentIGIJ:119568
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationIDAJ:31506
Biological ProcessGO:0018108peptidyl-tyrosine phosphorylationISOJ:164563
Biological ProcessGO:0016310phosphorylationIEAJ:60000
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationIGIJ:95803
Biological ProcessGO:0060045positive regulation of cardiac muscle cell proliferationIGIJ:95803
Biological ProcessGO:0045787positive regulation of cell cycleIMPJ:159839
Biological ProcessGO:0008284positive regulation of cell proliferationIDAJ:31506
Biological ProcessGO:0008284positive regulation of cell proliferationISOJ:73065
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:109722
Biological ProcessGO:0008284positive regulation of cell proliferationIGIJ:153198
Biological ProcessGO:0008284positive regulation of cell proliferationIMPJ:159839
Biological ProcessGO:0043406positive regulation of MAP kinase activityISOJ:164563
Biological ProcessGO:0043410positive regulation of MAPK cascadeISOJ:164563
Biological ProcessGO:0090080positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathwayIGIJ:153198
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIGIJ:107406
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationIMPJ:132412
Biological ProcessGO:0002053positive regulation of mesenchymal cell proliferationISOJ:155856
Biological ProcessGO:0045666positive regulation of neuron differentiationISOJ:164563
Biological ProcessGO:0010976positive regulation of neuron projection developmentISOJ:155856
Biological ProcessGO:0010976positive regulation of neuron projection developmentIGIJ:170083
Biological ProcessGO:0010863positive regulation of phospholipase C activityISOJ:164563
Biological ProcessGO:0045944positive regulation of transcription from RNA polymerase II promoterISOJ:155856
Biological ProcessGO:0046777protein autophosphorylationISOJ:164563
Biological ProcessGO:0006468protein phosphorylationIEAJ:72247
Biological ProcessGO:0060665regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signalingIDAJ:140258
Biological ProcessGO:0042127regulation of cell proliferationIMPJ:78879
Biological ProcessGO:0042127regulation of cell proliferationISOJ:155856
Biological ProcessGO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligandIMPJ:102949
Biological ProcessGO:2001239regulation of extrinsic apoptotic signaling pathway in absence of ligandIMPJ:132412
Biological ProcessGO:0010468regulation of gene expressionIMPJ:142755
Biological ProcessGO:0048378regulation of lateral mesodermal cell fate specificationIGIJ:119568
Biological ProcessGO:0051930regulation of sensory perception of painISOJ:155856
Biological ProcessGO:0072091regulation of stem cell proliferationISOJ:155856
Biological ProcessGO:0007435salivary gland morphogenesisIMPJ:79832
Biological ProcessGO:0007605sensory perception of soundIMPJ:95895
Biological ProcessGO:0019827stem cell maintenanceISOJ:155856
Biological ProcessGO:0001657ureteric bud developmentIGIJ:107078
Biological ProcessGO:0060979vasculogenesis involved in coronary vascular morphogenesisTASJ:169941
Biological ProcessGO:0021847ventricular zone neuroblast divisionIMPJ:159839

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IAS Inferred from ancestral seqeuence
  IBA Inferred from biological aspect of ancestor
  IBD Inferred from biological aspect of descendant
  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IKR Inferred from key residues
  IMP Inferred from mutant phenotype
  IMR Inferred from missing residues
  IPI Inferred from physical interaction
  IRD Inferred from rapid divergence
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Obsolete Evidence Code: Not Recorded

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory